Search the Archives           Subscribe           About this News Service           Reader Comments

Archived updates for Thursday, August 24, 2006

Referenced Patent Leads to Specific Exclusion Exception to DOE

In Cook Biotech Inc., et al. v. Acell, Inc., et al. (August 18, 2006) the Federal Circuit relied upon text incorporated-by-reference from a second patent as part of the intrinsic evidence for construing the term "urinary bladder submucosa (UBS) delaminated from both the abluminal muscle layers and at least the luminal portion of the tunica mucosa." as exclusing tunica propria and basement membrane

According to Wikipedia, the wall of the urinary bladder consists of three layers:
  1. Mucosa, in this instance 'transitional epithelium' & lamina propria (a thin vascular layer of areolar connective tissue beneath the epithelium)
  2. Detrusor Muscle that consists of an inner and outer longitudinal layer and a middle circular layer of smooth muscle
  3. Fibrous Adventitia and the visceral peritoneum (basement membrane?) lie on superior surface.
The "BACKGROUND AND SUMMARY OF THE INVENTION" section disclosed that "[t]he wall of the urinary bladder is composed of the following layers: the tunica mucosa (including a transitional epithelium layer and the tunica propria), a submucosa layer, up to three layers of muscle and the adventitia (a loose connective tissue layer)?listed in thickness crossection from luminal to abluminal sides." The "DETAILED DESCRIPTION OF THE INVENTION" section went on to explain:
The preparation of UBS from a segment of urinary bladder is similar to the procedure for preparing intestinal submucosa detailed in U.S. Patent No. 4,902,508, the disclosure of which is expressly incorporated herein by reference. A segment of urinary bladder tissue is first subjected to abrasion using a longitudinal wiping motion to remove both the outer layers (particularly the abluminal smooth muscle layers) and the luminal portions of the tunica mucosa layers?the epithelial layers). The resulting submucosa tissue has a thickness of about 80 micrometers, and consists primarily (greater than 98%) of a cellular, eosinophilic staining (H&E stain) extracellular matrix material.
According to the opinion by Circuit Judge Prost,

That paragraph makes clear that “the luminal portions of the tunica mucosa layers” were defined by the patentee as the “epithelial layers” and that “the
procedure for preparing intestinal submucosa” as detailed in the ’508 patent is expressly incorporated by reference into the ’389 patent specification. . . .

The term "epithelial layers" may arguably be subject to two interpretations. On the one hand, it refers to "layers" which appears to reflect that it was meant to encompass more than just the transitional epithelium layer, i.e., the transitional epithelium layer and the tunica propria layer, the only other layer that the ’389 patent teaches is part of the tunica mucosa. See id. at col. 1, ll. 51-52. On the other hand, as recognized by the district court, the epithelium in the urinary bladder is made up of multiple layers of epithelial cells. Markman Order, slip op. at 10. Even accepting that the disclosure in the ’389 patent specification itself is less than clear as to which interpretation is correct, the second important disclosure of the ’389 specification is dispositive. As noted, the ’389 patent specification expressly incorporates by reference the procedure for preparing intestinal submucosa from the ’508 patent. . . .

The ’389 patent’s corporation by reference of the ’508 patent’s procedure for preparing intestinal submucosa, in combination with the ’508 patent’s disclosure pertaining to which tissue layers are removed by that procedure, leads to the conclusion that the patentee’s definition of the claim term as reflected in the ’389 patent as the epithelial layers and in the ’508 patent as the lamina epithelialis mucosa and its lamina propria was intended to refer to the same structures, i.e., the lamina epithelialis mucosa (or transitional epithelium layer), the basement membrane, and the lamina propria.

Relying on a medical dictionary, the district court recognized that the tunica mucosa comprises the epithelium, basement membrane, lamina propria mucosae, and lamina muscularis mucosae. The court then rejected ACell’s proposed construction that "the luminal portion of the tunica musoca" means the epithelial cells (i.e., the transitional epithelium), the basement membrane, and the lamina propria because the term "would not require the entire tunica mucosa including the basement , slip op. at 11. membrane, tunica propria and all epithelial cells to be removed as ACell contends."

That statement by the district court reflects that it believed ACell’s proposed construction of that term encompassed the entire tunica mucosa, rather than just "the luminal portion" as the claim requires. The district court’s reasoning, however, overlooks the fact that ACell’s construction permits the retention of the lamina muscularis mucosae layer of the tunica mucosa. This construction is consistent with both the medical dictionary’s list of layers that comprise the tunica mucosa, and the teachings of the ’508 patent, which specifically refer to that layer as "layer E" of the tunica mucosa. ’508 patent, col. 3, ll. 14-15. As this discussion indicates, ACell’s proposed construction does not require removal of the entire tunica mucosa as the district court’s opinion suggests, but rather removal of only a portion of the tunica mucosa.

The district court also relied upon extrinsic evidence in the form of testimony from a Dr. Harbin who convinced the court that there was no compelling reason on the part of Cook to remove the basement membrane, lamina propria, or any other non-cellular component of the bladder wall layers. Markman Order, slip op. at 11. In light of the discussion above, however, such extrinsic evidence cannot override the patentee’s definition of the term contained in the intrinsic evidence of the ’389 and ’508 patent disclosures.

Therefore, we construe "the luminal portion of the tunica mucosa" to mean "the lamina epithelialis mucosa (or transitional epithelium layer), the basement membrane, and the lamina propria."

The court went on to conclude that applying appellees’ theory of equivalence with respect to asserted claims would violate a corollary to the ‘all limitations rule[,]’ . . . that ‘the concept of equivalency cannot embrace a structure that is specifically excluded from the scope of the claims.

The ACell Vet™ product consists of basement membrane and tunica propria, two tissue layers specifically excluded from the claimed composition by delaminating “the luminal portion of the tunica mucosa.” A claim that specifically excludes an element cannot through a theory of equivalence be used to capture a
composition that contains that expressly excluded element without violating the
“all limitations rule.” Permitting appellees to assert such a theory of equivalence would effectively remove the requirement that the urinary bladder submucosa be delaminated from “the luminal portion of the tunica mucosa." Thus, there is "no . . . material issue for the jury to resolve," see Warner-Jenkinson Co., Inc. v. Hilton Davis Chem. Co., 520 U.S. 17, 39 n.8 (1997), and a judgment of non-infringement under the doctrine of equivalents with respect to the asserted claims of the ’389 patent is appropriate.
    (27)comment(s)     translate     More Updates     Send    


Blogger Leona said...

Each time I used to always check blog posts within the first hours in the break of day, because I like to get information increasingly more. best sitation service

December 24, 2014 3:13 AM  
Anonymous Model Baju Batik Pria Lengan Pendek Terbaru 2015 said...

Good post. It is really help to us. Its give us lots of interest and pleasure. Its opportunity are so fantastic and working style so speedy. Its really a good article. It gives me lots of pleasure and interest.

March 25, 2015 2:06 AM  
Anonymous Pest Control said...

Good article.. Thanks for the information.
Cotton Bud
Marine Contractor

May 21, 2015 1:06 AM  
Blogger Meiqing Xu said...

cheap jordans
louis vuitton
pandora charms
oakley sunglasses
ray ban sungalss
celine outlet
abercrombie & fitch
kobe bryant shoes 2015
coach outlet stores
ray ban outlet
jordan retro
michael kors
coach factorty outlet
ray bans
michael kors
louis vuitton uk
jordan 6 black infrared 2015
michael kors handbags
celine outlet
oakley vault
louis vuitton outlet
fitflops clearance
louis vuitton handbags
christian louboutin
ray ban sunglasses
louis vuitton outlet
cheap jordans
burberry outlet online
christian louboutin shoes
gucci shoes
timberland boots
michael kors outlet
nike air max
coach factory outlet online
coach factory outlet
oakley vault
coach outlet
louis vuitton outlet
true religion sale
ray ban sunglasses

June 24, 2015 2:08 AM  
Anonymous Parfum said...

Hugo Boss Orange Man
Calvin Klein Eternity Women
Escada Ocean Lounge Women
Calvin Klein One Man
Bvlgari Jasmin Noir Women
Calvin Klein Eternity Man
Nina Ricci Ricci Ricci Mademoiselle
Calvin Klein Euphoria Blossom

January 30, 2016 11:47 AM  
Anonymous resep said...

Resep Masakan Sederhana
Resep Jus Tomat
Resep kue bolu kukus lapis
Resep donat labu kuning
Resep donat tanpa telur
Resep donat mini
Resep daging sapi
Resep Nasi Kuning
Resep Tahu Ranjau
Resep Pempek Dos
Resep bakso sapi
Resep ikan bakar
Resep martabak manis mini
Resep durian goreng
Resep donat praktis
Resep mie goreng
Resep telur pindang kecap
Resep semur telur kentang
Resep sayur asem betawi
Resep risoles isi sayuran
Resep sayur lodeh
Resep donat dunkin
Resep kue lapis tepung beras
Resep kolak kacang hijau ubi
Resep ayam bakar
Resep martabak manis bogasari
Resep Nugget ikan tuna tenggiri
Resep Nasi goreng seafood

February 18, 2016 6:43 AM  
Anonymous juna said...

Resep siomay bandung
Resep Nugget sayur
Resep perkedel jagung
Resep Kue nastar
Resep martabak manis bandung
Resep capcay kuah
Resep kue kastengel
Resep rendang padang
Resep donat kentang
Resep kue kering coklat
Resep soto ayam
Resep kue macaroon
Resep semur daging kentang
Resep Kolak pisang
Resep kue nastar
Resep tongseng kambing
Resep bubur kacang hijau madura
Resep ayam goreng mentega
Resep Brownies kukus
Resep ayam bakar
Resep capcay goreng
Resep sop ayam
Resep rempeyek kacang kedelai
Resep cah kangkung
Resep perkedel kentang

February 18, 2016 8:03 AM  
Blogger Zheng junxai5 said...

nike free 5.0
michael kors outlet
cheap ray ban sunglasses
air jordan femme
christian louboutin outlet
vans outlet
replica rolex watches
hollister clothing
coach outlet
tory burch outlet online
christian louboutin sale
juicy couture
coach outlet
air jordan shoes
oakley canada
michael kors handbags
michael kors outlet clearance
michael kors handbags
rolex watches
toms outlet
coach outlet store online clearances
michael kors handbags
coach outlet online
ladies cartier watches
nike trainers sale
coach factory outlet online
copy watches
discount jordans
christian louboutin shoes
coach factory outlet
coach factory outlet
oakley outlet
louis vuitton outlet online
louis vuitton handbags
red bottom shoes
michael kors outlet
kate spade outlet
louis vuitton purses
nfl jerseys

June 12, 2016 10:30 PM  
Blogger Ethel Graff said...

good one of the most important thing when it involves your child and Sealy Soybean Foam-Core I additionally took a picture of my kid sleeping & standing on it and nice.

February 09, 2017 5:51 AM  
Blogger Ethel Graff said...

good The application has actually gained popularity kodi apk Kodi application has actually been downloaded on nice.

February 11, 2017 2:44 AM  
Blogger whitegeorge said...

good with rooted tool. And also this application could not function for the unable to continue with your important work just because nice.

March 20, 2017 6:59 AM  
Blogger dai nguyen van said...

รอยสัก รวมรอยสัก สวยๆ รอยสักดารา รอยสักผู้ชาย เท่ๆ ใหม่ๆ
เปลี่ยนรหัส wifi tot
วิธีเปลี่ยนรหัส wifi
cach doi mat khau wifi


March 26, 2017 10:07 PM  
Blogger raybanoutlet001 said...

nike huarache
ralph lauren outlet
fitflops shoes
ugg outlet
fitflops sale
nike free run
omega watches sale
ugg boots
rolex replica watches
ralph lauren uk

July 08, 2017 2:35 AM  
Blogger happy 123 said...

yeezy boost 350
nike air force 1
adidas ultra boost
longchamp bags
nike roshe one
nike air zoom
adidas ultra boost
nike huarache
kyrie 3
adidas stan smith

July 29, 2017 9:40 PM  
Blogger happy 123 said...

nike huarache
ray ban sunglasses outlet
eagles jerseys
yeezy boost 350 white
jimmy choo shoes
oakley sunglasses
michael kors bags
ugg boots
michael kors handbags
ugg boots

August 02, 2017 1:32 AM  
Blogger aaa kitty20101122 said...

longchamp bags
vibram fivefingers
michael kors handbags
adidas stan smith
yeezy boost
nike air force
kobe 9
links of london
nike polo shirts

August 16, 2017 9:47 PM  
Blogger 郑佳颖 said...

adidas yeezy
longchamp longchamps
nike air force 1
yeezy shoes
light up shoes
timberland outlet
lebron 14
patriots jerseys
adidas nmd
adidas nmd r1

September 23, 2017 2:53 AM  
Blogger Love Kpop said...

I'm puzzled with lots of exercises. I was afraid I could not do the right time despite my hard work. I need a support person.

September 25, 2017 12:36 AM  
Blogger adidas nmd said...

gucci outlet
gucci borse
hugo boss outlet
instyler max 2
kate spade outlet
kate spade outlet
kate spade handbags
kate spade handbags
kate spade handbags
longchamp outlet

November 15, 2017 3:06 AM  
Blogger qqqqqq said...

cheap jordans
vans outlet
ysl bags
nike zoom
roshe run
adidas nmd
kobe 9
adidas outlet online
nike hyperdunk 2017
adidas online shop

January 23, 2018 3:00 AM  
Blogger Lilyh Gibsonc said...

cheap nfl jerseys
adidas nmd
adidas superstar
nike roshe uk
michael kors outlet online
ferragamo belts
nike hyperdunk 2017
nike air huarache
jordan shoes
tom ford eyewear

March 08, 2018 9:19 PM  
Blogger chenlili said...

pandora jewelry
michael kors outlet
pandora charms outlet
nmd adidas
pandora charms
pandora jewelry
pandora charms
coach outlet
ralph lauren uk
mlb jerseys

March 20, 2018 11:28 PM  
Anonymous Cara Mengobati Luka Tanpa Bekas said...

Thanks For Sharing The Information

Tips Untuk Mengatasi Kram Otot
Tips Mengobati Sakit/Nyeri Pinggang
Obat Untuk Menghilangkan Jerawat Bruntusan
Pengobatan Tradisional Sembuhkan Varises
Cara Mengobati Penyakit Kulit Lyme
Tips Untuk Mengobati Abses Anus

April 03, 2018 2:21 AM  
Blogger Fghkfhk Dfgaert said...

polo ralph lauren
fitflops sale
salomon shoes
ray ban sunglasses
chrome hearts
canada goose
nike factory outlet
ray ban sunglasses
los angeles lakers

April 09, 2018 3:35 AM  
Anonymous Pengobatan Alternatif Patah Tulang/Fraktur said...

This information is very useful. thank you for sharing. and I will also share information about health through the website

Obat Alami Menurunkan tekanan Darah Tinggi
Obat Penyakit kulit Eksim
Obat Benjolan Di Ketiak
Pengobatan Alami Tuntaskan Keputihan
Cara Mengatasi asam Lambung
Cara Mengobati Usus Buntu
Cara Mengobati Sinusitis

April 15, 2018 9:55 PM  
Blogger Yaro Gabriel said...

michael kors outlet
nike store uk
mulberry bags
cheap jordans
canada goose outlet
hornets jerseys
reebok trainers
denver broncos jerseys
christian louboutin outlet
coach outlet online

May 31, 2018 10:52 PM  
Blogger Yaro Gabriel said...

simulation shoes
mulberry outlet
kate spade outlet
le coq sportif shoes
coach outlet
michael kors outlet
supra shoes
isabel marant outlet
oakley sunglasses
mulberry bags

July 12, 2018 5:33 AM  

Post a Comment

<< Home